(AP Photo/Jed Jacobsohn)

SANTA CLARA, Calif. (AP) The San Francisco 49ers lost quarterback Jimmy Garoppolo to a season-ending left foot injury Sunday, dealing a big blow to one of the NFL's top teams.

Garoppolo got hurt on the opening drive of a 33-17 win over the Miami Dolphins and will need to undergo surgery that will sideline him for the remainder of the season.

"It's pretty crushing. We know what Jimmy's been through, how hard he's worked at this," coach Kyle Shanahan said after the game. "That was a really cool game, just as a team and all the stuff that went on throughout the game and just be able to overcome some things. So it's such a special win. But definitely mixed emotions hearing about Jimmy."

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