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| BNP Paribas WTA Finals Singapore | ||
| Surface: Hard | Date: Oct. 21 - Oct. 28 | Seed: 3 |
| Round | Opponent | W / L | Result |
| Round Robin | Sloane Stephens | Loss | 5-7, 6-4, 1-6 4-6, 7-5, 4-6 3-6, 0-0 Retired |
| Round Robin | Angelique Kerber | Loss | 5-7, 6-4, 1-6 4-6, 7-5, 4-6 3-6, 0-0 Retired |
| Round Robin | Kiki Bertens | Loss | 5-7, 6-4, 1-6 4-6, 7-5, 4-6 3-6, 0-0 Retired |
| China Open | ||
| Surface: Hard | Date: Sep. 29 - Oct. 7 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Zarina Diyas | Win | 6-4, 6-3 |
| Second Round | Danielle Collins | Win | 6-1, 6-0 |
| Third Round | Julia Goerges | Win | 6-1, 6-2 |
| Quarterfinals | Shuai Zhang | Win | 3-6, 6-4, 7-5 |
| Semifinals | Anastasija Sevastova | Loss | 4-6, 4-6 |
| Toray Pan Pacific Open | ||
| Surface: Hard | Date: Sep. 17 - Sep. 23 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Dominika Cibulkova | Win | 6-2, 6-1 |
| Quarterfinals | Barbora Strycova | Win | 6-3, 6-4 |
| Semifinals | Camila Giorgi | Win | 6-2, 6-3 |
| Final | Karolina Pliskova | Loss | 4-6, 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 27 - Sep. 9 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Laura Siegemund | Win | 6-3, 6-2 |
| Second Round | Julia Glushko | Win | 6-2, 6-0 |
| Third Round | Aliaksandra Sasnovich | Win | 6-0, 6-0 |
| Fourth Round | Aryna Sabalenka | Win | 6-3, 2-6, 6-4 |
| Quarterfinals | Lesia Tsurenko | Win | 6-1, 6-1 |
| Semifinals | Madison Keys | Win | 6-2, 6-4 |
| Final | Serena Williams | Win | 6-2, 6-4 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 12 - Aug. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Maria Sakkari | Loss | 3-6, 6-7 (8-10) |
| Coupe Rogers presentee par Banque Nationale | ||
| Surface: Hard | Date: Aug. 6 - Aug. 12 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Carla Suarez Navarro | Loss | 6-7 (2-7), 2-6 |
| Citi Open | ||
| Surface: Hard | Date: Jul. 30 - Aug. 5 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bernarda Pera | Win | 6-2, 7-6 (7-4) |
| Second Round | Magda Linette | Loss | 2-6, 6-3, 3-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 2 - Jul. 15 | Seed: 18 |
| Round | Opponent | W / L | Result |
| First Round | Monica Niculescu | Win | 6-4, 6-1 |
| Second Round | Katie Boulter | Win | 6-3, 6-4 |
| Third Round | Angelique Kerber | Loss | 2-6, 4-6 |
| Nature Valley Classic | ||
| Surface: Grass | Date: Jun. 18 - Jun. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Katie Boulter | Win | 6-1, 6-2 |
| Second Round | Dalila Jakupovic | Loss | 3-6, 0-0 Retired |
| Nature Valley Open | ||
| Surface: Grass | Date: Jun. 11 - Jun. 17 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Sachia Vickery | Win | 3-6, 6-1, 6-2 |
| Second Round | Denisa Allertova | Win | 6-3, 6-2 |
| Quarterfinals | Mihaela Buzarnescu | Win | 6-4, 6-1 |
| Semifinals | Ashleigh Barty | Loss | 3-6, 4-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 27 - Jun. 10 | Seed: 21 |
| Round | Opponent | W / L | Result |
| First Round | Sofia Kenin | Win | 6-2, 7-5 |
| Second Round | Zarina Diyas | Win | 6-4, 7-5 |
| Third Round | Madison Keys | Loss | 1-6, 6-7 (7-9) |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 13 - May 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Victoria Azarenka | Win | 6-0, 6-3 |
| Second Round | Simona Halep | Loss | 1-6, 0-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 5 - May 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Shuai Zhang | Loss | 1-6, 5-7 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 2 - Apr. 8 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Jennifer Brady | Win | 6-4, 6-4 |
| Second Round | Laura Siegemund | Win | 6-3, 7-6 (10-8) |
| Third Round | Julia Goerges | Loss | 6-7 (4-7), 3-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Serena Williams | Win | 6-3, 6-2 |
| Second Round | Elina Svitolina | Loss | 4-6, 2-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 7 - Mar. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Maria Sharapova | Win | 6-4, 6-4 |
| Second Round | Agnieszka Radwanska | Win | 6-3, 6-2 |
| Third Round | Sachia Vickery | Win | 6-3, 6-3 |
| Fourth Round | Maria Sakkari | Win | 6-1, 5-7, 6-1 |
| Quarterfinals | Karolina Pliskova | Win | 6-2, 6-3 |
| Semifinals | Simona Halep | Win | 6-3, 6-0 |
| Final | Daria Kasatkina | Win | 6-3, 6-2 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 19 - Feb. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kristina Mladenovic | Win | 6-2, 6-2 |
| Second Round | Anett Kontaveit | Win | 6-2, 7-6 (7-5) |
| Quarterfinals | Elina Svitolina | Loss | 2-6, 4-6 |
| Qatar Total Open | ||
| Surface: Hard | Date: Feb. 12 - Feb. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Katerina Siniakova | Win | 6-4, 6-0 |
| Second Round | Anastasija Sevastova | Loss | 4-6, 1-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kristina Kucova | Win | 7-5, 6-2 |
| Second Round | Elena Vesnina | Win | 7-6 (7-4), 6-2 |
| Third Round | Ashleigh Barty | Win | 6-4, 6-2 |
| Fourth Round | Simona Halep | Loss | 3-6, 2-6 |
| Hobart International | ||
| Surface: Hard | Date: Jan. 7 - Jan. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Yulia Putintseva | Loss | 3-6, 3-6 |
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