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| Roland Garros | ||
| Surface: Red Clay | Date: May 22 - Jun. 5 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Chloe Paquet |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 8 - May 15 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Shuai Zhang | Win | 6-2, 6-0 |
| Third Round | Jessica Pegula | Win | 6-1, 6-4 |
| Quarterfinals | Amanda Anisimova | Win | 4-6, 6-3, 6-2 |
| Semifinals | Iga Swiatek | Loss | 2-6, 1-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 28 - May 8 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Amanda Anisimova | Loss | 2-6, 6-3, 4-6 |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 18 - Apr. 24 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Bianca Andreescu | Win | 6-1, 3-6, 6-2 |
| Quarterfinals | Anett Kontaveit | Win | 6-4, 3-6, 6-1 |
| Semifinals | Paula Badosa | Win | 7-6 (7-5), 6-4 |
| Final | Iga Swiatek | Loss | 2-6, 2-6 |
| Credit One Charleston Open | ||
| Surface: Green Clay | Date: Apr. 4 - Apr. 10 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Alison Riske | Win | 7-6 (7-3), 6-4 |
| Third Round | Amanda Anisimova | Loss | 6-3, 4-6, 3-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 3 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Irina-Camelia Begu | Loss | 4-6, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 9 - Mar. 20 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jasmine Paolini | Loss | 6-2, 3-6, 3-6 |
| Qatar TotalEnergies Open | ||
| Surface: Hard | Date: Feb. 20 - Feb. 26 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Alize Cornet | Win | 6-2, 6-2 |
| Third Round | Jil Teichmann | Win | 6-2, 6-1 |
| Quarterfinals | Iga Swiatek | Loss | 2-6, 3-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 14 - Feb. 19 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Marta Kostyuk | Win | 6-4, 6-1 |
| Second Round | Petra Kvitova | Loss | 4-6, 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 17 - Jan. 30 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Storm Sanders | Win | 5-7, 6-3, 6-2 |
| Second Round | Xinyu Wang | Win | 1-6, 6-4, 6-2 |
| Third Round | Marketa Vondrousova | Win | 4-6, 6-3, 6-1 |
| Fourth Round | Kaia Kanepi | Loss | 7-5, 2-6, 6-7 (7-10) |
| Adelaide International 2 | ||
| Surface: Hard | Date: Jan. 10 - Jan. 15 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Rebecca Peterson | Loss | 7-5, 1-6, 5-7 |
| Adelaide International 1 | ||
| Surface: Hard | Date: Jan. 3 - Jan. 9 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Kaja Juvan | Loss | 6-7 (6-8), 1-6 |
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